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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.6 No.2
- 발행연도
- 2001.6
- 수록면
- 122 - 125 (4page)
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초록· 키워드
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A potential mechanism through which the jujube extract might produce a cholesterol-lowering effect was compared with that of tangerine peel extract in vivo. Two extracts were prepared using ethanol. Male rats were fed a high cholesterol (1%, w/w) lab chow with jujube extract (1.2%, w/w) or tangerine peel extract (6.3%, w/w) for 3 weeks. Activities of hepatic HMG-CoA reductase (289.6±12.9 and 296.7±11.6 nmole/min/㎎ vs. 347.9±17.5 nmole/min/㎎) and ACAT (554.8±18.2 and 451.7±19.4 nmole/min/㎎ vs. 602.6±21.4 nmole/min/㎎) were significantly lowered by both supplements compared to the control group. These two supplements also substantially reduced the concentrations of plasma cholesterol (103.3±15.9 and 101.6±19.4 ㎎/dL vs. 141.6±18.1 ㎎/dL) and triglyceride (61.3±5.5 and 55.5±3.9 ㎎/dL vs. 96.0±4.2 ㎎/dL). The inhibition of HMG-CoA reductase resulting from the supplementation of jujube or tangerine extracts could count for the reduction in plasma cholesterol. Accordingly, lipid-lowering action of both supplements appears to be similar in high-cholesterol fed rats.
목차
Abstract
INTRODUCTION
METHODS AND MATERIALS
RESULTS
DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
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