지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.9
- 수록면
- 360 - 367 (8page)
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초록· 키워드
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In this study, we investigated the effects of total ginseng saponin (TGS) on the cutaneous wound healing process using histological analysis. A total of 24 ICR mice, 5-weeks-old, were used for all in vivo experiments. Mice were divided into control and TGS-treated groups and four equidistant 1-cm full-thickness dorsal incisional wounds were created. The wounds were extracted at days 1, 3, 5, and 7 post-injury for histomorphometrical analysis including wound area and contracture measurements, keratinocyte migration rate, and calculation of infiltrating inflammatory cells. The results showed that the wound area was smaller and keratinocyte migration rate was higher in the TGS-treated group than that of the control group from days 3 to 7. Inflammatory cells in the TGS-treated group at days 1 and 3 were reduced compared to the control group. Wound contraction in the TGS-treated group was greater than in the control group on days 3 to 5, and collagen deposition in the TGS-treated group was higher than in the control group during wound healing. The results indicate a beneficial effect of TGS when used to treat skin wounds.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
참고문헌 (33)
참고문헌 신청
1. [학술지(정기간행물)] - Stephens P / 2002 / The cellular proliferative phase of the wound repair process / J Wound Care 11 : 253 ~ 261
2. [학술지(정기간행물)] - Werner S / 2007 / Keratinocyte-fibroblast interactions in wound healing / J Invest Dermatol 127 : 998 ~ 1008
3. [학술지(정기간행물)] - Blazso G / 2004 / Pycnogenol accelerates wound healing and reduces scar formation / Phytother Res 18 : 579 ~ 581
4. [학술지(정기간행물)] - Guclu-Ustundag O / 2007 / Saponins: properties, applications and processing / Crit Rev Food Sci Nutr 47 : 231 ~ 258
5. [학술지(정기간행물)] - Baumann E / 2000 / Hemolysis of human erythrocytes with saponin affects the membrane structure / Acta Histochem 102 : 21 ~ 35
2. [학술지(정기간행물)] - Werner S / 2007 / Keratinocyte-fibroblast interactions in wound healing / J Invest Dermatol 127 : 998 ~ 1008
3. [학술지(정기간행물)] - Blazso G / 2004 / Pycnogenol accelerates wound healing and reduces scar formation / Phytother Res 18 : 579 ~ 581
4. [학술지(정기간행물)] - Guclu-Ustundag O / 2007 / Saponins: properties, applications and processing / Crit Rev Food Sci Nutr 47 : 231 ~ 258
5. [학술지(정기간행물)] - Baumann E / 2000 / Hemolysis of human erythrocytes with saponin affects the membrane structure / Acta Histochem 102 : 21 ~ 35
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UCI(KEPA) : I410-ECN-0101-2013-524-000762298