As a review of literature about lifelong sports througy physical activity effect on Alzheimer`s disease prevention, following conclusions are drawn. Physical activities enhance brain health of both patients and non-patients and the workout of the whole body is more efficient. For those who got Alzheimer`s disease(AD) and mild cognitive impairment(MCI) that physical activities ameliorates the conservation of brain. The workout is a good means of alleviating and preventing the aging process and neurode generative diseases. The low-intense or mid-intense jogging is good for the prevention of Alzheimer`s disease in terms of memory improvement and other low-intense physical activities such as walking, stroll, riding a bicycle, swimming or playing golf are also beneficial. It was more high reprocuction rate nerve cell, occure to increase of estrogen. Regular physical activity is defined to be 30 minutes a day and 3 times a week. It alleviates nerve cell degradation and ameliorates neural plasticity for Alzheimer`s disease affected patients. Conscious manual exercise improves learning capabilities and concentration and it prevents dementia for all categories of people ranging from infants to adults and seniors. It provides opportunities for seniors and people who are not seniors to understand, respect and communicate meaningfully with the old age and prevents the decline of physical functions caused by the lack of physical activities and Alzheimer`s disease by promoting the development of physical, emotional, social, functional characteristics and by extending schools` physical education to the lifelong sports in order for people to make a lifestyle.