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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 29 - 36 (8page)
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Abstract
Objectives The purpose of this study was to assess the ability of two new calcium silicate-based pulp-capping materials (Biodentine and BioAggregate) to induce healing in a rat pulp injury model and to compare them with mineral trioxide aggregate (MTA).
Materials and Methods Eighteen rats were anesthetized, cavities were prepared and the pulp was capped with either of ProRoot MTA, Biodentine, or BioAggregate. The specimens were scanned using a high-resolution micro-computed tomography (micro-CT) system and were prepared and evaluated histologically and immunohistochemically using dentin sialoprotein (DSP).
Results On micro-CT analysis, the ProRoot MTA and Biodentine groups showed significantly thicker hard tissue formation (p < 0.05). On H&E staining, ProRoot MTA showed complete dentin bridge formation with normal pulpal histology. In the Biodentine and BioAggregate groups, a thick, homogeneous hard tissue barrier was observed. The ProRoot MTA specimens showed strong immunopositive reaction for DSP.
Conclusions Our results suggest that calcium silicate-based pulp-capping materials induce favorable effects on reparative processes during vital pulp therapy and that both Biodentine and BioAggregate could be considered as alternatives to ProRoot MTA.
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참고문헌 (42)
참고문헌 신청
Dominquez MS / 2003 / Histological and scanning electron microscopy assessment of various vital pulp-therapy materials / J Endod 29:324~333
Torabinejad M / 1999 / Clinical applications of mineral trioxide aggregate / J Endod 25:197~205
de Souza V / 1974 / Treatment of the inflamed dental pulp / Aust Dent J 19:191~196
Eskandar i zadeh A / 2011 / A comparative study on dental pulp response to calcium hydroxide, white and grey mineral trioxide aggregate as pulp capping agents / J Conserv Dent 14:351~355
Faraco IM Jr / 2001 / Response of the pulp of dogs to capping with mineral trioxide aggregate or a calcium hydroxide cement / Dent Traumatol 17:163~166
Torabinejad M / 1999 / Clinical applications of mineral trioxide aggregate / J Endod 25:197~205
de Souza V / 1974 / Treatment of the inflamed dental pulp / Aust Dent J 19:191~196
Eskandar i zadeh A / 2011 / A comparative study on dental pulp response to calcium hydroxide, white and grey mineral trioxide aggregate as pulp capping agents / J Conserv Dent 14:351~355
Faraco IM Jr / 2001 / Response of the pulp of dogs to capping with mineral trioxide aggregate or a calcium hydroxide cement / Dent Traumatol 17:163~166
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