지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 196 - 202 (7page)
이용수
초록· 키워드
오류제보하기
Objective The aim of this study was to investigate the prevalence of orofacial clefts and identify the characteristics of other birth defects associated with orofacial clefts in Korea.
Methods This study used data from the Congenital Anomaly Survey conducted by the Korea Institute for Health and Social Affairs. The survey was conducted on birth defects documented during 2005 to 2006 in 2,348 medical institutes in Korea. This study was performed using data from medical insurance claims of the National Health Insurance Corporation. The prevalence of orofacial clefts was defined as the number of cases per 10,000 live births.
Results Among the 883,184 live births, 25,335 infants had birth defects, which included 980 infants with orofacial clefts. The prevalence of total orofacial clefts in the total live births was 11.09 per 10,000, accounting for 3.9% of all birth defects. The most common orofacial cleft was cleft palate only (n=492), followed by cleft lip only (n=245) and cleft lip with cleft palate (n=243), with prevalence rates of 5.57, 2.77, 2.75 per 10,000 live births, respectively. While malformations of the circulatory system; digestive system; eyes, ears, face, and neck; and musculoskeletal system were most frequently encountered among infants with a cleft lip with or without a cleft palate, anomalies of most organ systems were notably observed among infants with cleft palate only.
Conclusion The prevalence of orofacial clefts in Korea was similar or slightly lower than that of other countries. This study informs present status of orofacial clefts and gives baseline data to lay the foundation stone for Korea’s registry system of orofacial clefts.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Canfield MA. / 2006 / National estimates and race/ethnicspecific variation of selected birth defects in the United States, 1999-2001 / Birth Defects Res A Clin Mol Teratol 76
Cordero JF. / 1994 / Finding the causes of birth defects / N Engl J Med 331 : 48 ~ 49
Derijcke A. / 1996 / The incidence of oral clefts : a review / Br J Oral Maxillofac Surg 34 : 488 ~ 494
Fraser FC. / 1970 / The genetics of cleft lip and cleft palate / Am J Hum Genet 22 : 336 ~ 352
Genisca AE. / 2009 / Orofacial clefts in the National Birth Defects Prevention Study, 1997-2004 / Am J Med Genet A 149A : 1149 ~ 1158
Cordero JF. / 1994 / Finding the causes of birth defects / N Engl J Med 331 : 48 ~ 49
Derijcke A. / 1996 / The incidence of oral clefts : a review / Br J Oral Maxillofac Surg 34 : 488 ~ 494
Fraser FC. / 1970 / The genetics of cleft lip and cleft palate / Am J Hum Genet 22 : 336 ~ 352
Genisca AE. / 2009 / Orofacial clefts in the National Birth Defects Prevention Study, 1997-2004 / Am J Med Genet A 149A : 1149 ~ 1158
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