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- 2021.5
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이 논문의 연구 히스토리 (3)
2021
Determination of the metabolic alterations of short-chain fatty acids and TCA cycle intermediates in human plasma with gastric disorders using GC-MS/MS
Wonwoong Lee
,
You Lee Kim
,
Jongki Hong
한국분석과학회 학술대회
2021.11
학술대회자료
Profiling of steroid hormones in human plasma by MAD-GC-MS/MS for diagnosis of gastric disorders
Wonwoong Lee
,
Bong Chul Chung
,
Jongki Hong
한국분석과학회 학술대회
2021.05
학술대회자료
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Steroid hormones are associated to cellular signaling, inflammatory immune responses, and reproductive functions, and their metabolism alterations can incur various diseases. In particular, quantitative profiling of steroids in plasma of gastric cancer patients can provide information to understand development of gastric cancer, since both sex hormones and glucocorticoids might be related to the pathological mechanisms of gastric cancer. Here, we developed a gas chromatography-tandem mass spectrometry-dynamic multiple reaction monitoring (GC-MS/MS-dMRM) method combined with solid-phase extraction (SPE) and microwave-assisted derivatization (MAD) to determine 20 endogenous steroids in human plasma. In this study, SPE and MAD conditions were optimized with respect to elution solution and volumes and irradiation power and time, respectively. The optimized SPE enabled effective cleanup and extraction for profiling of steroid hormones in human plasma samples. The MAD could improve laborious and time-consuming derivatization procedure, since dielectric heating using ... 전체 초록 보기
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Simultaneous profiling of bile acids, histidine, and histamine in gastric juice by LC-MS/MS combined with serial derivatization: diagnosis of gastric cancer
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Assessment of gastric disorders via simultaneous profiling of histidine and free bile acid metabolism in gastric juice using LC-MS/MS coupled with serial derivatization
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낮은 GWP를 가진 CxF2xO 을 이용한 SiO2 식각 공정 특성에 관한 연구
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Assessing the progression of gastric cancer via profiling of SCFAs and TCA cycle intermediates in human plasma using GC-MS/MS
한국분석과학회 학술대회
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Assessing the progression of gastric cancer via profiling of SCFAs and TCA cycle intermediates in human plasma using GC-MS/MS
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