지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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The objective of this study was to fabricate a novel hydrophobic stent for reducing restenosis by employing electron beam equipment. The stent was fabricated from a CoCr alloy tube by using a femtosecond laser and was treated with argon plasma. Subsequently, the stent’s surface specification changed from hydrophilic to hydrophobic. Application of the electron beam offers several advantages such as a short processing time, whole surface reforming, and enhancement of material properties. As the surface of the stent was rendered hydrophobic, it can provide equivalent or enhanced mechanical properties and greater functionality with a higher radial force at the extended stent in a blood vessel. The obtained results corresponding to the mechanical properties indicate that the contact angle increased to approximately 130o , and the radial force increased to approximately 3 N. Furthermore, cell culture experiments were conducted for verifying whether cells were cultured on the surface-modified CoCr surface. Based on the obtained results, it is believed that an effective reduction in the restenosis of inserted vascular stents is possible.
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참고문헌 (8)
참고문헌 신청
Levine / 1995 / Restenosis following coronary angioplasty : clinical presentations and therapeutic options / Clin. Cardiol. 18(12):693~703
P. Vermeersch / 2007 / Increased late mortality after sirolimus-eluting stents versus bare-metal stents in diseased saphenous vein grafts:results from the randomized DELAYED RRISC Trial / J. Am. Coll. Cardiol. 50(3):261~267
S. Bangalore / 2013 / Bare metal stents, durable polymer drug eluting stents, and biodegradable polymer drug eluting stents for coronary artery disease:mixed treatment comparison meta-analysis / Br. Med. J., 347:f6625(1)~f6625(19)
I. H. Bae / 2018 / Novel Polymer-Free Everolimus Eluting Stent Fabricated using Femtosecond Laser Improves Re-endothelialization and Anti-infammatio / Sci. Rep 8(1):7383(1)~7383(11)
배인호 / 2020 / Mechanical and physio-biological properties of peptide-coated stent for re-endothelialization / 생체재료학회지 24(1):110~118
P. Vermeersch / 2007 / Increased late mortality after sirolimus-eluting stents versus bare-metal stents in diseased saphenous vein grafts:results from the randomized DELAYED RRISC Trial / J. Am. Coll. Cardiol. 50(3):261~267
S. Bangalore / 2013 / Bare metal stents, durable polymer drug eluting stents, and biodegradable polymer drug eluting stents for coronary artery disease:mixed treatment comparison meta-analysis / Br. Med. J., 347:f6625(1)~f6625(19)
I. H. Bae / 2018 / Novel Polymer-Free Everolimus Eluting Stent Fabricated using Femtosecond Laser Improves Re-endothelialization and Anti-infammatio / Sci. Rep 8(1):7383(1)~7383(11)
배인호 / 2020 / Mechanical and physio-biological properties of peptide-coated stent for re-endothelialization / 생체재료학회지 24(1):110~118
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