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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 479 - 484 (6page)
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초록· 키워드
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The ultimate goal of regenerative medicine is to regain or restore the damaged or lost function of tissues and organs. Several therapeutic strategies are currently being explored to achieve this goal. From the point of view of regenerative medicine, extracellular vesicles (EVs) are exceptionally attractive due to the fact that they can overcome the limitations faced by many cell therapies and can be engineered according to their purpose through various technical modifications. EVs are biological nanoscale vesicles naturally secreted by all forms of living organisms, including prokaryotes and eukaryotes, and act as vehicles of communication between cells and their surrounding environment. Over the past decade, EVs have emerged as a new therapeutic agent for various diseases and conditions owing to their multifaceted biological functions. This is reflected by the number of publications on this subject found in the Web of Science database, which currently exceeds 12,300, over 85% of which were published within the last decade, demonstrating the increasing global trends of this innovative field. The reviews collected in this special issue provide an overview of the different approaches being explored in the use of EVs for regenerative medicine.
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참고문헌 (32)
참고문헌 신청
H Rashed M / 2017 / Exosomes : from garbage bins to promising therapeutic targets / Int J Mol Sci 18:538
Gurung S / 2021 / The exosome journey : from biogenesis to uptake and intracellular signalling / Cell Commun Signal 19:47
Witwer KW / 2019 / Extracellular vesicles or exosomes? On primacy, precision, and popularity influencing a choice of nomenclature / J Extracell Vesicles 8:1648167
Zhuang WZ / 2021 / Mesenchymal stem/stromal cell-based therapy : mechanism, systemic safety and biodistribution for precision clinical applications / J Biomed Sci 28:28
Lee JY / 2016 / Microvesicles from brain-extract-treated mesenchymal stem cells improve neurological functions in a rat model of ischemic stroke / Sci Rep 6:33038
Gurung S / 2021 / The exosome journey : from biogenesis to uptake and intracellular signalling / Cell Commun Signal 19:47
Witwer KW / 2019 / Extracellular vesicles or exosomes? On primacy, precision, and popularity influencing a choice of nomenclature / J Extracell Vesicles 8:1648167
Zhuang WZ / 2021 / Mesenchymal stem/stromal cell-based therapy : mechanism, systemic safety and biodistribution for precision clinical applications / J Biomed Sci 28:28
Lee JY / 2016 / Microvesicles from brain-extract-treated mesenchymal stem cells improve neurological functions in a rat model of ischemic stroke / Sci Rep 6:33038
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