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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 575 - 590 (16page)
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BACKGROUND: Biopolymeric in situ hydrogels play a crucial role in the regenerative repair and replacement of infected or injured tissue. They possess excellent biodegradability and biocompatibility in the biological system, however only a few biopolymeric in situ hydrogels have been approved clinically. Researchers have been investigating new advancements and designs to restore tissue functions and structure, and these studies involve a composite of biometrics, cells and a combination of factors that can repair or regenerate damaged tissue. METHODS: Injectable hydrogels, cross-linking mechanisms, bioactive materials for injectable hydrogels, clinically applied injectable biopolymeric hydrogels and the bioimaging applications of hydrogels were reviewed. RESULTS: This article reviews the different types of biopolymeric injectable hydrogels, their gelation mechanisms, tissue engineering, clinical applications and their various in situ imaging techniques. CONCLUSION: The applications of bioactive injectable hydrogels and their bioimaging are a promising area in tissue engineering and regenerative medicine. There is a high demand for injectable hydrogels for in situ imaging.
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참고문헌 (73)
참고문헌 신청
Campoccia D / 1998 / Semisynthetic resorbable materials from hyaluronan esterification / Biomaterials 19:2101~2127
Prestwich GD / 1998 / Controlled chemical modification of hyaluronic acid: synthesis, applications, and biodegradation of hydrazide derivatives / J Control Release 53:93~103
Park KM / 2017 / Encyclopedia of radicals in chemistry, biology, and materials
Hoffman AS / 2012 / Hydrogels for biomedical applications / Adv Drug Deliv Rev 64:18~23
Atala A / 1993 / Injectable alginate seeded with chondrocytes as a potential treatment for vesicoureteral reflux / J Urol 150:745~747
Prestwich GD / 1998 / Controlled chemical modification of hyaluronic acid: synthesis, applications, and biodegradation of hydrazide derivatives / J Control Release 53:93~103
Park KM / 2017 / Encyclopedia of radicals in chemistry, biology, and materials
Hoffman AS / 2012 / Hydrogels for biomedical applications / Adv Drug Deliv Rev 64:18~23
Atala A / 1993 / Injectable alginate seeded with chondrocytes as a potential treatment for vesicoureteral reflux / J Urol 150:745~747
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