지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 240 - 246 (7page)
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초록· 키워드
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Background: Anemia is associated with various poor clinical outcomes in chronic kidney disease patients. The aim of this study was to investigate the relationship between anemia and the initiation degree and time of dialysis in type 2 diabetic nephropathy patients. Methods: This observational retrospective study included 130 type 2 diabetic nephropathy patients in Korea. The existence of anemia, the degree and time of dialysis initiation were reviewed. Clinical characteristics and variables were also compared. Results: The levels of hemoglobin and serum creatinine were significantly correlated with the dialysis initiation (P<0.05) during the 10-year follow-up period. Patients with anemia showed rapid decline of renal function, causing significantly more dialysis initiation (54.1% vs. 5.4%, P<0.05) compare to the patients without anemia. Average time to initiate dialysis in patients with anemia was 45.1 months (range, 8.0 to 115.8 months), which was significantly faster than that (68.3 months [range, 23.3 to 108.8 months]) in patients without anemia (P<0.01). The risk to dialysis initiation was significantly increased in patients with anemia compared to the patients without anemia (adjusted hazard ratio, 8.1; 95% confidence interval, 2.4 to 27.0; P<0.05). Conclusion: Anemia is associated with rapid decline of renal dysfunction and faster initiation of dialysis in diabetic nephropathy patients. Therefore, clinicians should pay an earlier attention to anemia during the management of diabetes.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
Mogensen CE / 1984 / Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes / N Engl J Med 310:356~360
USRDS / 2003 / the United States Renal Data System / Am J Kidney Dis 42(6 Suppl 5):1~230
Valmadrid CT / 2000 / The risk of cardiovascular disease mortality associated with microalbuminuria and gross proteinuria in persons with older-onset diabetes mellitus / Arch Intern Med 160:1093~1100
Peterson JC / 1995 / Blood pressure control, proteinuria, and the progression of renal disease. The Modification of Diet in Renal Disease Study / Ann Intern Med 123:754~762
Jones RL / 1981 / Hematologic alterations in diabetes mellitus / Am J Med 70:339~352
USRDS / 2003 / the United States Renal Data System / Am J Kidney Dis 42(6 Suppl 5):1~230
Valmadrid CT / 2000 / The risk of cardiovascular disease mortality associated with microalbuminuria and gross proteinuria in persons with older-onset diabetes mellitus / Arch Intern Med 160:1093~1100
Peterson JC / 1995 / Blood pressure control, proteinuria, and the progression of renal disease. The Modification of Diet in Renal Disease Study / Ann Intern Med 123:754~762
Jones RL / 1981 / Hematologic alterations in diabetes mellitus / Am J Med 70:339~352
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