메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Jeon Jun Ho (Division of High-risk Pathogens Korea Disease Control and Prevention Agency Cheongju Korea) Choi Chi-Hwan (Division of Zoonotic and Vector Borne Disease Research Korea Disease Control and Prevention Agency) Kim Jeong Hyun (Division of Zoonotic and Vector Borne Disease Control Korea Disease Control and Prevention Agency C) Hyun Junghee (Division of Emerging Infectious Disease Response Korea Disease Control and Prevention Agency Cheong) Choi Eun-Sun (Division of High-risk Pathogens Korea Disease Control and Prevention Agency Cheongju Korea) Choi Sang-Yoon (Division of High-risk Pathogens Korea Disease Control and Prevention Agency Cheongju Korea) Shin Yong-Woo (Division of High-risk Pathogens Korea Disease Control and Prevention Agency Cheongju Korea) Pyo Seong Wook (Division of High-risk Pathogens Korea Disease Control and Prevention Agency Cheongju Korea) Kim Dae-Won (Division of Zoonotic and Vector Borne Disease Research Korea Disease Control and Prevention Agency) Kang Byung Hak (Division of High-risk Pathogens Korea Disease Control and Prevention Agency Cheongju Korea) Park Young Joon (Director for Epidemiological Investigation Analysis Korea Disease Control and Prevention Agency Che) Rhie Gi-eun (Division of High-risk Pathogens Korea Disease Control and Prevention Agency Cheongju Korea)
저널정보
대한진단검사의학회 Annals of Laboratory Medicine Annals of Laboratory Medicine 제41권 제5호
발행연도
2021.9
수록면
489 - 492 (4page)
DOI
10.3343/alm.2021.41.5.489

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Botulism is a neuroparalytic disease caused by a neurotoxin produced by Clostridium botulinum. This study aimed to genetically characterize C. botulinum strain isolated from the first case of infant botulism in Korea reported on June 17, 2019. We isolated C. botulinum strain CB-27 from a stool sample of the patient and analyzed the toxin types and toxin gene cluster compositions of the strain using a mouse bioassay, real-time PCR, and genome sequencing. Toxin gene cluster analysis showed that strain CB-27 possesses a C. botulinum neurotoxin type A harboring an unexpressed B gene. Although the nucleotide and amino acid sequences of toxin genes as well as the toxin gene cluster arrangements in strain CB-27 were identical to those of the known strain CDC_69094, the total nucleotide sequences of the toxin gene clusters of CB-27 differed from those of CDC_69094 by 0.47%, indicating genetic diversity of toxin gene clusters of CB-27 among other previously reported C. botulinum strains. To our knowledge, this is the first description of a C. botulinum strain with two separate toxin gene clusters in Korea.

목차

등록된 정보가 없습니다.

참고문헌 (2)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0