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논문 기본 정보

자료유형
학술대회자료
저자정보
Young-Woo Kim (National Cancer Center)
저널정보
대한종양외과학회 대한임상종양학회 학술대회지 대한종양외과학회 2021 Seoul International Symposium of Surgical Oncology [초록집]
발행연도
2021.6
수록면
122 - 124 (3page)

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초록· 키워드

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In 2010, the World Health Organization (WHO) endorsed PBM as a worldwide trend that should be embraced by all medical communities (WHA 63.12). PBM is a multidisciplinary, individualized approach to optimize patient outcome through the systematic implementation of effective and safe blood management strategies, including the minimization or elimination of unnecessary exposure to transfusions.

Patients with gastric cancer are particularly vulnerable to the effects of anemia mainly due to the complications of the disease itself and the physiological disruptions brought about by surgery. Anemia is one of the most common hematologic consequences after gastrectomy. Iron deficiency, as a cause of postgastrectomy anemia, the exact pathogenesis of iron deficiency after gastrectomy remains to be elucidated; nevertheless, it is postulated to be dependent primarily on the impaired iron absorption due to rapid intestinal transit and operative bypass of the duodenum, which is the main area of iron absorption. In addition, factors such as operative blood loss and decreased dietary intake after surgery can disturb iron homeostasis by further depleting the body’s iron stores

The compelling evidence against perioperative transfusion and anemia has fostered a growing interest for the Patient Blood Management (PBM) concept, a multidisciplinary, multimodal strategy, encompassing the entire length of the patient’s clinical management, with an objective of curtailing inappropriate blood transfusion use and enhancing patients’ outcomes. Deeply entrenched in this approach are the three pillar tenets of peri-operative hematopoietic optimization, attenuation of perioperative coagulopathy and blood loss, and improvement of patient’s physiological tolerance to postoperative anemia. Over the years, PBM has gradually evolved, allowing a broader application in other clinical settings including surgery and oncology.

Pillar 1: Managing Pre-operative Anemia in Gastric Cancer Patients

The majority of gastric cancer surgeries are elective procedures; hence, treatment of preoperative iron deficiency anemia should be promptly instituted prior to the scheduled operation. Once the diagnosis^_@span style=color:#999999 ^_# ... ^_@/span^_#^_@a href=javascript:; onclick=onClickReadNode('NODE10593460');fn_statistics('Z354','null','null'); style='color:#999999;font-size:14px;text-decoration:underline;' ^_#전체 초록 보기^_@/a^_#

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