Accumulation characteristics and correlation analysis of five ginsenosides with different cultivation ages from different regions

Dan Xiao; Hao Yue; Yang Xiu; Xiuli Sun; YiBo Wang; ShuYing Liu

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자료유형: 학술저널

저자정보: Dan Xiao (Chinese Academy of Sciences) Hao Yue (Changchun University of Chinese Medicine) Yang Xiu (Changchun University of Chinese Medicine) Xiuli Sun (Changchun University of Chinese Medicine) YiBo Wang (Changchun University of Chinese Medicine) ShuYing Liu (Chinese Academy of Sciences)

저널정보: 고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.39 No.4

발행연도: 2015.10

수록면: 338 - 344 (7page)

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Background: Ginseng (the roots of Panax ginseng Meyer) is a well-known traditional Oriental medicine and is now widely used as a health food. It contains several types of ginsenosides, which are considered the major active medicinal components of ginseng. It has recently been reported that the qualitative and quantitative properties of ginsenosides found in ginseng may differ, depending on cultivation regions, ages, species, and so on. Therefore, it is necessary to study these variations with respect to cultivation ages and regions.
Methods: In this study, 3-6-yr-old roots of P. ginseng were collected from three different cultivation regions. The contents of five ginsenosides (Rb1, Rd, Rc, Re, and Rgl) were measured by rapid resolution liquid chromatography coupled with quadrupleetime-of-flight mass spectrometry. The KruskaleWallis Rank sum test and multiple t test were used for comparative analysis of the data to evaluate the dynamic changes in the accumulation of these ginsenosides affected by cultivation regions and ages.
Results: The content and composition of ginsenosides varied significantly among specimens collected from different cultivation regions and having different cultivation ages. For all samples, the content of Rg1 and Re ginsenosides increases with age and this rate of increase is different for each sample. The contents of Rb1, Rc, and Rd varied with cultivation ages in samples from different cultivation regions; especially, Rb1 from a 6-yr-old root showed approximately twofold variation among the samples from three cultivation regions. Furthermore, the content of Rb1 highly correlated with that of Rd (r=0.89 across all locations and ages).
Conclusion: In our study, only the contents of ginsenosides Rg1 and Re were affected by the root age. Ginsenosides Rb1, Rc, and Rd varied widely with ages in samples from different cultivation regions.

#cultivation #ginsenosides #harvest age #Panax ginseng #regions

참고문헌 (25)

참고문헌 신청

[학술지(정기간행물)] - Pu Z / 2011 / The evaluation of contents of nine ginsenoside monomers in ginseng hairy roots by high performance liquid chromatography (HPLC) / J Med Plants Res 5 : 5513 ~ 5516

[학술지(정기간행물)] - Shu-ping C / 2011 / HPLC simultaneous determination of nine ginsenosides in Shenmai injection / Chinese J Pharm Anal 31 (3) : 476 ~ 478

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[학술지(정기간행물)] - Kim N / 2011 / Metabolomic approach for age discrimination of Panax ginseng using UPLC-Q-Tof MS / J Agric Food Chem 59 : 10435 ~ 10441

[학술지(정기간행물)] - Ruan CC / 2010 / Isolation and characterization of a new ginsenoside from the fresh root of Panax ginseng / Molecules 15 : 2319 ~ 2325

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이 논문의 저자 정보

Dan Xiao

소속기관 Changchun University of Technology

주요연구분야 의약학 > 기타 의약학

논문수 3 이용수 9

Hao Yue