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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.3
- 수록면
- 205 - 214 (10page)
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초록· 키워드
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Background: This article aims to compare and analyze the contents of ginsenosides in ginseng of different plant ages from different localities in China.
Methods: In this study, 77 fresh ginseng samples aged 2-4 years were collected from 13 different cultivation regions in China. The content of eight ginsenosides (Rg₃, Rc, Rg₁, Rf, Rb₂, Rb₁, Re, and Rd) was determined using rapid resolution liquid chromatography coupled with quadrupole-time-of-flight tandem mass spectrometry (RRLC-Q-TOF MS/MS) to comparatively evaluate the influences of cultivation region and age.
Results: Ginsenoside contents differed significantly depending on age and cultivation region. The contents of ginsenosides Re, Rc, Rg₁, Rg₃, and Rf increased with cultivation age, whereas that of ginsenoside Rb₁ peaked in the third year of cultivation. Moreover, the highest ginsenoside content was obtained from Changbai (19.36 mg/g) whereas the lowest content was obtained from Jidong (12.05 mg/g). Ginseng from Jilin Province contained greater total ginsenosides and was richer in ginsenoside Re than ginseng of the same age group in Heilongjiang and Liaoning provinces, where Rb₁ and Rg₁ contents were relatively high.
Conclusion: In this study, RRLC-Q-TOF MS/MS was used to analyze ginsenoside contents in 77 ginseng samples aged 2-4 years from different cultivation regions. These patterns of variation in ginsenoside content, which depend on harvesting location and age, could be useful for interested parties to choose ginseng products according to their needs.
Methods: In this study, 77 fresh ginseng samples aged 2-4 years were collected from 13 different cultivation regions in China. The content of eight ginsenosides (Rg₃, Rc, Rg₁, Rf, Rb₂, Rb₁, Re, and Rd) was determined using rapid resolution liquid chromatography coupled with quadrupole-time-of-flight tandem mass spectrometry (RRLC-Q-TOF MS/MS) to comparatively evaluate the influences of cultivation region and age.
Results: Ginsenoside contents differed significantly depending on age and cultivation region. The contents of ginsenosides Re, Rc, Rg₁, Rg₃, and Rf increased with cultivation age, whereas that of ginsenoside Rb₁ peaked in the third year of cultivation. Moreover, the highest ginsenoside content was obtained from Changbai (19.36 mg/g) whereas the lowest content was obtained from Jidong (12.05 mg/g). Ginseng from Jilin Province contained greater total ginsenosides and was richer in ginsenoside Re than ginseng of the same age group in Heilongjiang and Liaoning provinces, where Rb₁ and Rg₁ contents were relatively high.
Conclusion: In this study, RRLC-Q-TOF MS/MS was used to analyze ginsenoside contents in 77 ginseng samples aged 2-4 years from different cultivation regions. These patterns of variation in ginsenoside content, which depend on harvesting location and age, could be useful for interested parties to choose ginseng products according to their needs.
목차
ABSTRACT
1. Introduction
2. Materials and methods
3. Results and discussion
4. Conclusions
References
참고문헌 (26)
참고문헌 신청
Nah SY / 1997 / Ginseng; recent advances and trends / J Ginseng Res 21:1~12
Yujie Chen / 2017 / Determination of ginsenosides in Asian and American ginsengs by liquid chromatographyequadrupole/time-of-flight MS: assessing variations based on morphological characteristics / Journal of Ginseng Research 41(1):10~22
Choi KT / 2008 / Botanical characteristics Pharmacological effects and medicinal components of Korean Panax ginseng C. A. Meyer / Acta Pharmacol Sinica 29:1109~1118
Xie JT / 2005 / Anti-diabetic effect of ginsenoside Re in ob/ob mice / Biochim Et Biophys Acta Mol Basis Dis 1740:319~325
Metori K / 1997 / The preventive effect of ginseng with duzhong leaf on protein metabolism in aging / Biol Pharmaceut Bull 20:237~242
Yujie Chen / 2017 / Determination of ginsenosides in Asian and American ginsengs by liquid chromatographyequadrupole/time-of-flight MS: assessing variations based on morphological characteristics / Journal of Ginseng Research 41(1):10~22
Choi KT / 2008 / Botanical characteristics Pharmacological effects and medicinal components of Korean Panax ginseng C. A. Meyer / Acta Pharmacol Sinica 29:1109~1118
Xie JT / 2005 / Anti-diabetic effect of ginsenoside Re in ob/ob mice / Biochim Et Biophys Acta Mol Basis Dis 1740:319~325
Metori K / 1997 / The preventive effect of ginseng with duzhong leaf on protein metabolism in aging / Biol Pharmaceut Bull 20:237~242
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UCI(KEPA) : I410-ECN-0101-2020-524-000504506