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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.6
- 수록면
- 277 - 287 (11page)
이용수
초록· 키워드
오류제보하기
Background: Temperature is an essential condition in red ginseng processing. The pharmacological activities of red ginseng under different steam temperatures are significantly different.
Methods: In this study, an ultrahigh-performance liquid chromatography quadrupole time-of-flight tandem mass spectrometry was developed to distinguish the red ginseng products that were steamed at high and low temperatures. Multivariate statistical analyses such as principal component analysis and supervised orthogonal partial least squared discrimination analysis were used to determine the influential components of the different samples.
Results: The results showed that different steamed red ginseng samples can be identified, and the characteristic components were 20-gluco-ginsenoside Rf, ginsenoside Re, ginsenoside Rg1, and malonylginsenoside Rb1 in red ginseng steamed at low temperature. Meanwhile, the characteristic components in red ginseng steamed at high temperature were 20R-ginsenoside Rs3 and ginsenoside Rs4. Polar ginsenosides were abundant in red ginseng steamed at low temperature, whereas higher levels of less polar ginsenosides were detected in red ginseng steamed at high temperature.
Conclusion: This study makes the first time that differences between red ginseng steamed under different temperatures and their ginsenosides transformation have been observed systematically at the chemistry level. The results suggested that the identified chemical markers can be used to illustrate the transformation of ginsenosides in red ginseng processing.
Methods: In this study, an ultrahigh-performance liquid chromatography quadrupole time-of-flight tandem mass spectrometry was developed to distinguish the red ginseng products that were steamed at high and low temperatures. Multivariate statistical analyses such as principal component analysis and supervised orthogonal partial least squared discrimination analysis were used to determine the influential components of the different samples.
Results: The results showed that different steamed red ginseng samples can be identified, and the characteristic components were 20-gluco-ginsenoside Rf, ginsenoside Re, ginsenoside Rg1, and malonylginsenoside Rb1 in red ginseng steamed at low temperature. Meanwhile, the characteristic components in red ginseng steamed at high temperature were 20R-ginsenoside Rs3 and ginsenoside Rs4. Polar ginsenosides were abundant in red ginseng steamed at low temperature, whereas higher levels of less polar ginsenosides were detected in red ginseng steamed at high temperature.
Conclusion: This study makes the first time that differences between red ginseng steamed under different temperatures and their ginsenosides transformation have been observed systematically at the chemistry level. The results suggested that the identified chemical markers can be used to illustrate the transformation of ginsenosides in red ginseng processing.
목차
ABSTRACT
1. Introduction
2. Materials and methods
3. Results and discussion
4. Conclusion
References
참고문헌 (24)
참고문헌 신청
[학술지(정기간행물)] - Kennedy DO / 2003 / Ginseng: potential for the enhancement of cognitive performance and mood / Pharmacol Biochem Behav 75 : 687 ~ 700
[학술지(정기간행물)] - Coleman CI / 2003 / The effects of Panax ginseng on quality of life / J Clin Pharm Ther 28 : 5 ~ 15
[학술지(정기간행물)] - Jiao L / 2014 / Chemical and antihyperglycemic activity changes of ginseng pectin induced by heat processing / Carbohydr Polym 114 : 567 ~ 573
[학술지(정기간행물)] - Yang WZ / 2012 / A strategy for efficient discovery of new natural compounds by integrating orthogonal column chromatography and liquid chromatography/mass spectrometry analysis: its application in Panax ginseng, Panax quinquefolium and Panax notoginseng to characterize 437 potential new ginsenosides / Anal Chim Acta 739 : 56 ~ 66
[학술지(정기간행물)] - Wang Y / 2013 / Analgesic effects of glycoproteins from Panax ginseng root in mice / J Ethnopharmacol 148 : 946 ~ 950
[학술지(정기간행물)] - Coleman CI / 2003 / The effects of Panax ginseng on quality of life / J Clin Pharm Ther 28 : 5 ~ 15
[학술지(정기간행물)] - Jiao L / 2014 / Chemical and antihyperglycemic activity changes of ginseng pectin induced by heat processing / Carbohydr Polym 114 : 567 ~ 573
[학술지(정기간행물)] - Yang WZ / 2012 / A strategy for efficient discovery of new natural compounds by integrating orthogonal column chromatography and liquid chromatography/mass spectrometry analysis: its application in Panax ginseng, Panax quinquefolium and Panax notoginseng to characterize 437 potential new ginsenosides / Anal Chim Acta 739 : 56 ~ 66
[학술지(정기간행물)] - Wang Y / 2013 / Analgesic effects of glycoproteins from Panax ginseng root in mice / J Ethnopharmacol 148 : 946 ~ 950
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UCI(KEPA) : I410-ECN-0101-2018-524-003161140