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논문 기본 정보

자료유형
학술저널
저자정보
Jong-Hoon Kim (Chonbuk National University)
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.42 No.3
발행연도
2018.6
수록면
264 - 269 (6page)

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초록· 키워드

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Panax ginseng, also called Asian or Korean ginseng, has long been traditionally used in Korea and China to treat various diseases. The major active ingredients of P. ginseng are ginsenosides, which have been shown to have a variety of therapeutic effects, including antioxidation, anti-inflammatory, vasorelaxation, antiallergic, antidiabetic, and anticancer. To date, approximately 40 ginsenoside components have been reported. Current research is concentrating on using a single ginseng compound, one of the ginsenosides, instead of the total ginseng compounds, to determine the mechanisms of ginseng and ginsenosides. Recent in vitro and in vivo results show that ginseng has beneficial effects on cardiac and vascular diseases through efficacy, including antioxidation, control of vasomotor function, modulation of ion channels and signal transduction, improvement of lipid profiles, adjustment of blood pressure, improvement in cardiac function, and reduction in platelet adhesion. This review aims to provide valuable information on the traditional uses of ginseng and ginsenosides, their therapeutic applications in animal models and humans, and the pharmacological action of ginseng and ginsenosides.

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ABSTRACT
1. Introduction
2. Ginsenosides are the pharmacologically active components in ginseng
3. Ginsenosides modulate various ion channels
4. Ginsenosides modulate cellular signal transduction
5. Ginseng and ginsenosides improve antioxidant and blood circulation
6. Ginsenosides ameliorate vascular function
7. Ginseng and ginsenosides improve blood pressure
8. Ginseng and ginsenosides improve cardiac function
9. Ginseng and ginsenosides inhibit platelet aggregation
10. Ginseng and ginsenosides ameliorate lipid profile
11. Ginseng and ginsenosides prevent myocardial ischemia
12. Summary
References

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