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논문 기본 정보

자료유형
학술저널
저자정보
Muhammad Irfan (Kyungpook National University) Yi-Seong Kwak (Korean Ginseng cooperation) Chang-Kyun Han (Korean Ginseng cooperation) Sun Hee Hyun (Korean Ginseng cooperation) Man Hee Rhee (Kyungpook National University)
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.44 No.4
발행연도
2020.7
수록면
538 - 543 (6page)

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초록· 키워드

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Cardiovascular diseases are a rapidly growing epidemic with high morbidity and mortality. There is an urgent need to develop nutraceutical-based therapy with minimum side effects to reduce cardiovascular risk. Panax ginseng occupies a prominent status in herbal medicine for its various therapeutic effects against inflammation, allergy, diabetes, cardiovascular diseases, and even cancer, with positive, beneficial, and restorative effects. The active components found in most P. ginseng varieties are known to include ginsenosides, polysaccharides, peptides, alkaloids, polyacetylene, and phenolic compounds, which are considered to be the main pharmacologically active constituents in ginseng. P. ginseng is an adaptogen. That is, it supports living organisms to maintain optimal homeostasis by exerting effects that counteract physiological changes caused by physical, chemical, or biological stressors. P. ginseng possesses immunomodulatory (including both immunostimulatory and immunosuppressive), neuromodulatory, and cardioprotective effects; suppresses anxiety; and balances vascular tone. P. ginseng has an antihypertensive effect that has been explained by its vasorelaxant action, and paradoxically, it is also known to increase blood pressure by vasoconstriction and help maintain cardiovascular health. Here, we discuss the potential adaptogenic effects of P. ginseng on the cardiovascular system and outline a future research perspective in this area.

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ABSTRACT
1. Introduction
2. Blood pressure and vascular tone (antihypertensive and hypertensive effects)
3. Aphrodisiac properties (adaptogenic effects on physical and sexual performance)
4. Balance vasomotor function and cardiac protection
5. Antiplatelet effects
6. Blood viscosity and hemostasis
7. Antihyperlipidemic properties (antihyperlipidemic and antiobesity effect)
8. Alzheimer disease
9. Structure-activity relationship
10. Concluding remarks
11. Future perspectives
References

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